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 Monday, January 5, 2009
11:00 a.m.   Other Tri-Institutional Events
Functional Genomics, Experimental Models and Cancer

William C. Hahn, M.D., Ph.D., associate professor of medicine, Harvard Medical School and Dana-Farber Cancer Institute

 Tuesday, January 6, 2009
4:00 p.m.   Pharmacology Seminars
STAT Signaling in the Pathogenesis and Treatment of Cancer

David A. Frank, M.D., Ph.D., associate professor of medicine, Dana-Farber Cancer Institute

 Wednesday, January 7, 2009
11:00 a.m.   Cell Biology Seminars
The Many Faces of Fat: From Membrane Organization to Lipid Storage

Tobias Walther, Ph.D., group leader, organelle architecture and dynamics, Max Planck Institute of Biochemistry

12:00 p.m.   Seminars in Clinical Research
Inherited Bone Marrow Failure Syndromes

Farid Boulad, M.D., medical director, Pediatric Day Hospital, Memorial Sloan-Kettering Cancer Center

4:30 p.m.   MSKCC President's Research Seminar
Genetic Regulation of Genome Rearrangements in Yeast

Thomas Petes, Ph.D., professor and chair, department of molecular genetics and microbiology, Duke University School of Medicine

 Thursday, January 8, 2009
2:00 p.m.   Center for Studies in Physics and Biology Seminars
Confined Water, Hydrophobicity and Protein Stability in Vitro and in Vivo

Jeremy England, Ph.D., Stanford University

2:00 p.m.   Molecular Pharmacology and Chemistry Program
A Genetic Map of the S. Cerevisiae Phosphorylation Network

Dorothea Fiedler, Ph.D., postdoctoral fellow, department of cellular and molecular pharmacology, University of California, San Francisco

 Monday, January 12, 2009
11:00 a.m.   Other Tri-Institutional Events
Evolution in Cell Groups

Joao Xavier, postdoctoral fellow, Center for Systems Biology, Harvard University

7:00 p.m.   Club Meetings
Improvisational Theater Group
 Tuesday, January 13, 2009
4:00 p.m.   Center for Studies in Physics and Biology Seminars
How simple animals navigate gradients

Aravi Samuel, Ph.D., Assistant Professor, Harvard University

4:00 p.m.   Molecular Pharmacology and Chemistry Program
Reinventing Amide-bond Formation

Jeffrey Bode, Ph.D., associate professor of chemistry, University of Pennsylvania

 Wednesday, January 14, 2009
12:00 p.m.   Seminars in Clinical Research
To Be Announced
4:30 p.m.   MSKCC President's Research Seminar
Vesicular Traffic: Mechanism and Disease Connections

Randy Schekman, Ph.D., professor of cell and developmental biology, University of California, Berkeley

 Thursday, January 15, 2009
11:00 a.m.   Molecular Pharmacology and Chemistry Program
Small Molecule-mediated Signaling between Organisms

Rebecca Butcher, Ph.D., postdoctoral fellow, department of biological chemistry and molecular pharmacology, Harvard Medical School

11:00 a.m.   Other Tri-Institutional Events
How Protein Sequestration Generates a Flexible Ultrasensitive Response

Nicolas Buchler, Ph.D., postdoctoral fellow, Laboratory of Yeast Molecular Genetics, Rockefeller University

3:00 p.m.   Other Tri-Institutional Events
Center for Cell Engineering Second Annual Retreat

Rudolf Jaenisch, M.D., Whitehead Institute

Konrad Hochedlinger, Ph.D., Harvard University, Epigenetic Reprogramming and Induced Pluripotency

Lorenz Studer, M.D., MSKCC, Human Pluripotent Cells For Modeling Neural Development and Disease

8:00 p.m.   Harvey Society
Fundamental Units of Synaptic Communication Between Brain Cells

Richard Tsien, , il, Stanford University

 Friday, January 16, 2009
11:00 a.m.   Cell Biology Seminars
Assembly of the Mitotic Spindle Matrix, a Template for Coupling Cell Division and Cell Fate Choices?

Yixian Zheng, Ph.D., staff member, department of embryology, Carnegie Institution for Science; investigator, Howard Hughes Medical Institute

12:00 p.m.   Molecular Biology Seminars
Static and Dynamic Genome-wide Views of Yeast Chromatin

Oliver Rando, M.D., Ph.D., assistant professor, University of Massachusetts Medical School

 Monday, January 19, 2009
11:00 a.m.   Other Tri-Institutional Events
Deciphering the Function of Urm1, an Enigmatic Ubiquitin-related Modifier: An Unexpected Link to RNA Modification Pathways

Christian Schlieker, Ph.D., Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology

12:00 p.m.   Other Tri-Institutional Events
Identification, Molecular Characterization, Clinical Prognosis and Therapeutic Targeting of Human Bladder Tumor-initiating Cell Population

Keith Syson Chan, Ph.D., postdoctoral fellow, Stem Cell Biology and Regenerative Medicine Institute, Stanford University

7:00 p.m.   Club Meetings
Improvisational Theater Group
 Tuesday, January 20, 2009
2:00 p.m.   Center for Studies in Physics and Biology Seminars
Self-Assembly of Spherical Particles at Low N

Natalie Arkus, Ph.D., Harvard University

2:00 p.m.   Molecular Pharmacology and Chemistry Program
pHLIP Nanotechnology Platform for Cancer Imaging and Therapy

Yana Reshetnyak, Ph.D., assistant professor, department of physics, University of Rhode Island

4:00 p.m.   Pharmacology Seminars
Targeting Signaling Pathways in Head and Neck Cancer

Jennifer R. Grandis, M.D., vice chair for research, University of Pittsburgh Cancer Institute

 Wednesday, January 21, 2009
12:00 p.m.   Seminars in Clinical Research
Transcription and Signaling Pathways and Their Therapeutic Targeting in Melanoma

David Fisher, M.D., Ph.D., director, melanoma program, Dana-Farber Cancer Institute and Harvard University

12:00 p.m.   Club Meetings
Yeast Club
2:00 p.m.   Center for Studies in Physics and Biology Seminars
Understanding Quorum Sensing In Bacteria

Sidhartha Goyal, Ph.D., Princeton University

 Thursday, January 22, 2009
2:00 p.m.   Center for Studies in Physics and Biology Seminars
Optimization, Control and Flies: Quantitative Studies of Insect Flight

Gordon Berman, Ph.D., Cornell University

 Friday, January 23, 2009
12:00 p.m.   Other Tri-Institutional Events
BubR1 in Mitosis, Cancer and Aging

Jan van Deursen, Ph.D., professor of pediatrics and adolescent medicine and of biochemistry and molecular biology, Mayo Clinic

 Monday, January 26, 2009
12:00 p.m.   Other Tri-Institutional Events
GSK-3 as a Therapeutic Target in Cancer

Zhong Wang, Ph.D., postdoctoral fellow, department of pathology, Stanford University School of Medicine

1:30 p.m.   Other Tri-Institutional Events
CD4 T Cells: Fates, Functions, Faults

William Paul, M.D., chief, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health

2:00 p.m.   Cell Biology Seminars
Color Vision in Drosophila

Claude Desplan, Ph.D., professor, department of pathology, New York University

2:00 p.m.   Center for Studies in Physics and Biology Seminars
Geometric Phases in Stochastic Kinetics: New Design Principles in Molecular Robotics

Nikolai Sinitsyn, Ph.D., postdoctoral research associate, Center for Nonlinear Studies, Los Alamos National Laboratory

7:00 p.m.   Club Meetings
Improvisational Theater Group
 Tuesday, January 27, 2009
1:30 p.m.   Other Seminars
A Scientific Symposium in Memory of Joshua Lederberg
4:00 p.m.   Center for Studies in Physics and Biology Seminars
Action at a Distance in Eukaryotic Gene Regulation

Anirvan Sengupta, Ph.D., associate professor, Rutgers University

4:00 p.m.   Molecular Pharmacology and Chemistry Program
Elucidation of Molecular Foundation of Cancer: A Chemical Biology Approach

Weihong Tan, Ph.D., V.T. and Louis Jackson Professor of Chemistry and Physiology and associate director, Center for Research at the Bio/Nano Interface, University of Florida

7:00 p.m.   Other Meetings
Psoriasis Support Group
 Wednesday, January 28, 2009
10:30 a.m.   Other Tri-Institutional Events
Analyzing Cancer at the Single Cell Level

Cathy Shachaf, Ph.D., instructor in medicine, Donald E. and Delia B. Baxter Laboratory in Genetic Pharmacology, department of microbiology and immunology, Stanford University School of Medicine

12:00 p.m.   Seminars in Clinical Research
Monocytes, Dendritic Cells and the Resolution of Inflammation

Gwendalyn Randolph, Ph.D., associate professor, gene and cell medicine, Mount Sinai School of Medicine

12:15 p.m.   Thesis Presentations
Regulation of Heterochromatin Protein 1 by Phosphorylation of Histone H3 and the HP1 Hinge Domain

Holger Dormann, graduate fellow, Rockefeller University

2:00 p.m.   Other Tri-Institutional Events
Structural View of Nonsense-mediated mRNA Decay

Elena Conti, Ph.D., director, department of biochemistry and structural cell biology, Max Planck Institute of Biochemistry

4:30 p.m.   MSKCC President's Research Seminar
How Telomeres Protect Chromosome Ends

Titia de Lange, Ph.D., Leon Hess Professor and head, Laboratory of Cell Biology and Genetics, Rockefeller University

 Thursday, January 29, 2009
11:00 a.m.   Anderson Cancer Center Lecture Series
Molecular Mechanisms of RNA Degradation

Elena Conti, Ph.D., director, department of structural cell biology, Max Planck Institute of Biochemistry

6:00 p.m.   The Peggy Rockefeller Concerts
Peggy Rockefeller Concert Buffet
8:00 p.m.   The Peggy Rockefeller Concerts
Andrew von Oeyen, piano
Performing works by Bach, Andrew von Oeyen, Debussy, David Newman and Liszt
Andrew von Oeyen




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