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 Monday, December 1, 2008
1:30 p.m.   Other Tri-Institutional Events
The Spleen Marginal Zone and B Cell Repertoires

John Kearney, Ph.D., professor of microbiology, University of Alabama, Birmingham

2:00 p.m.   Cell Biology Seminars
Novel Gene Regulatory Mechanisms in Cartilage Development and Homeostasis

Mary B. Goldring, Ph.D., Senior Scientist, Laboratory for Cartilage Biology, Hospital for Special Surgery

7:00 p.m.   Other Arts Events
Improvisational Theater Group
 Tuesday, December 2, 2008
10:30 a.m.   Other Tri-Institutional Events
The Mechanisms of Evolution in Cell Populations and Cancer

Joao Xavier, postdoctoral fellow, Center for Systems Biology, Harvard University

2:00 p.m.   Center for Studies in Physics and Biology Seminars
Implicit Check-bits in Biology: the Iterative Use of Not-always-correct Rapid Neural Computation

John Hopfield, Ph.D., professor, Princeton University

2:00 p.m.   Other Seminars
Distinct Pathways of Regulating Gene Expression through Histone Phosphorylation and Ubiquitylation

Peter Cheung, Ph.D., scientist, Ontario Cancer Institute; Canada Research Chair in Chromatin Regulation, University of Toronto

4:00 p.m.   Molecular Pharmacology and Chemistry Program
Cell Death in Yeast: An Unexpected Model of Tumorigenesis

J. Marie Hardwick, Ph.D., The David Bodian Professor, department of molecular microbiology and immunology, The Johns Hopkins School of Medicine

 Wednesday, December 3, 2008
12:00 p.m.   Seminars in Clinical Research
NEAT 4 Live: Ending Obesity

James A. Levine, M.D., Ph.D., professor of medicine, Mayo Clinic

 Thursday, December 4, 2008
11:00 a.m.   Anderson Cancer Center Lecture Series
HIFs, Stem Cells and Tumor Progression

Celeste Simon, Ph.D., professor, University of Pennsylvania School of Medicine

12:00 p.m.   Biochemistry Lectures
Regulation of the Brush Border Na/H Exchanger NHE3: How a Transporter Works, a Story of Regulatory Complexes and Cytoskeleton

Mark Donowitz, M.D., LeBoff Professor of Medicine, The Johns Hopkins School of Medicine

7:00 p.m.   Other Seminars
The Darwin Beat: Reporting from the Frontiers of Evolution

Carl Zimmer

 Monday, December 8, 2008
10:30 a.m.   Other Tri-Institutional Events
Multi-scale Modeling of Cardiac Electrophysiology: Dynamic Heterogeneity, Conduction Block and Reentry

Jeffrey Fox, Ph.D., vice president, cardiovascular research, Gene Network Sciences

1:30 p.m.   Other Tri-Institutional Events
Properties of Homeostatic Memory CD8 T Cells

Stephen Jameson, Ph.D., professor, department of laboratory medicine and pathology, University of Minnesota Center for Immunology

7:00 p.m.   Other Arts Events
Improvisational Theater Group
 Tuesday, December 9, 2008
4:00 p.m.   Pharmacology Seminars
Targeting Signal Transduction Pathways in Glioblastoma

Ingo K. Mellinghoff, M.D., assistant attending and member, Memorial Sloan-Kettering Cancer Center

4:00 p.m.   Center for Studies in Physics and Biology Seminars
DeMISTifying the Brain: Dissecting the Function of Complex Neural Circuits

Alla Karpova, Ph.D., group leader, Janelia Farm Research Campus, Howard Hughes Medical Institute

 Wednesday, December 10, 2008
12:00 p.m.   Seminars in Clinical Research
Molecular Genetics of Autosomal Dominant Polycystic Kidney Disease

Sandro Rossetti, M.D., assistant professor of medicine, division of nephrology, Mayo Clinic

12:30 p.m.   Club Meetings
Yeast Club
6:00 p.m.   The Peggy Rockefeller Concerts
Peggy Rockefeller Buffet
8:00 p.m.   The Peggy Rockefeller Concerts
Susan Platts, mezzo-soprano; Brett Polegato, baritone; and Rena Sharon, piano

Susan Platts, Brett Polegato and Rena Sharon
 Thursday, December 11, 2008
2:00 p.m.   Other Tri-Institutional Events
NHERF1 - Modulator of the PI3K and Wnt/b-catenin Pathways in Cancer

Maria-Magdalena Georgescu, M.D., Ph.D., associate professor, departments of neuro-oncology and molecular genetics, University of Texas M.D. Anderson Cancer Center

4:30 p.m.   Molecular Pharmacology and Chemistry Program
Cancer Cell Metabolism: What Was Warburg Studying?

Craig Thompson, M.D., director, Abramson Cancer Center, and associate vice president, cancer services, University of Pennsylvania

 Friday, December 12, 2008
1:30 p.m.   Thesis Presentations
What is the Sound of One Ear Hearing? The Production of Spontaneous Otoacoustic Emissions

Michael Gelfand, biomedical fellow, Rockefeller University

 Monday, December 15, 2008
11:00 a.m.   Other Special Events
T-shirt Shop Holiday Sale
1:30 p.m.   Other Tri-Institutional Events
Initiation and Maintenance of TCR-β Allelic Exclusion

Michael Krangel, Ph.D., professor of immunology, Duke University

7:00 p.m.   Other Arts Events
Improvisational Theater Group
 Tuesday, December 16, 2008
10:00 a.m.   Thesis Presentations
Precious Bodily Fluids or: How I Learned to Stop Worrying and Love the Worm

Evan Macosko, biomedical fellow, Rockefeller University

4:00 p.m.   Molecular Pharmacology and Chemistry Program
Streamlining Synthesis via C-H Oxidation

Christina White, Ph.D., assistant professor of chemistry, University of Illinois

 Wednesday, December 17, 2008
12:00 p.m.   Seminars in Clinical Research
Fat Metabolism in Obesity

Samuel Klein, M.D., professor of medicine and nutritional science and director, Center for Human Nutrition, Washington University School of Medicine

 Friday, December 19, 2008
12:00 p.m.   Other Tri-Institutional Events
Emerging Roles of Centrosomes in Ciliopathies and Asymmetric Events during Mitosis

Stephen Doxsey, Ph.D., professor, program in molecular medicine, University of Massachusetts Medical School

 Monday, December 22, 2008
2:00 p.m.   Molecular Pharmacology and Chemistry Program
Noncanonical Assembly-line Biosynthesis: The Story of Coronatine Biogenesis

Eric Streiter, Ph.D., American Cancer Society Postdoctoral Fellow, department of biological chemistry and molecular pharmacology, Harvard Medical School





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