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 Monday, April 3, 2017
1:30 p.m.   Other Tri-Institutional Events
Diversification of the TCRa and TCRd Repertoires by Chromatin Regulation in One and Three Dimensions

Michael Krangel, Ph.D., Mary Bernheim Professor and Chair, department of immunology, Duke University Medical Center

 Tuesday, April 4, 2017
4:00 p.m.   Center for Studies in Physics and Biology Seminars
Deep Linearity in Adaptation and Evolution: Macroscopic Theory, Microscopic Simulation, and Bacterial Experiments

Kunihiko Kaneko, Ph.D., professor, department of basic science, University of Tokyo

 Thursday, April 6, 2017
2:00 p.m.   Other Tri-Institutional Events
Insights into the Brain from Protein–RNA Interactions

Gene Yeo, Ph.D., professor, department of cellular and molecular medicine, University of California, San Diego

4:00 p.m.   Cell Biology Seminars
Dissecting and Targeting Mechanisms of Apoptotic Deregulation in Cancer

Loren Walensky, M.D., Ph.D., associate professor, department of pediatric oncology, director, Harvard/MIT MD-PhD Program, Harvard Medical School

7:30 p.m.   The Peggy Rockefeller Concerts
Elliot Madore, baritone 
 Friday, April 7, 2017
12:00 p.m.   Thesis Presentations
Compromising the 20S Proteasome Complex Activates a Quality Control Pathway to Mitigate Proteotoxic Stress

Irit Shachrai, graduate fellow, The Rockefeller University

3:45 p.m.   Friday Lecture Series
The 16th Annual Wiley Prize in Biomedical Sciences
The Wiley Prize

Joachim Frank, Ph.D., investigator, Howard Hughes Medical Institute; professor, department of biochemistry and molecular biophysics, Columbia University; distinguished professor, The State University of New York at Albany

Richard Henderson, Ph.D., scientist and programme leader, MRC Laboratory of Molecular Biology

Marin van Heel, Ph.D., emeritus professor, Institute of Biology Leiden (NeCEN); visiting professor, Imperial College London; visiting professor, Brazilian National Nanotechnology Laboratory—LNNano/CNPEM

 Saturday, April 8, 2017
9:30 a.m.   Other Campus Events
Sense 2 Synapse 2017
Biology of Sensory Transduction and Neuronal Processing
 Monday, April 10, 2017
10:00 a.m.   Thesis Presentations
Home Sweet Home: Epigenetic Paths of Stem Cells In and Out of Their Niche

Rene Adam, graduate fellow, The Rockefeller University

1:30 p.m.   Other Tri-Institutional Events
Immune Processing and Recognition of Tumors

Max Krummel, Ph.D., professor, department of pathology, University of California, San Francisco

2:00 p.m.   Other Tri-Institutional Events
Thoughts on Druggability: Lessons from Challenging Targets

Percy Carter, Ph.D., vice president and head of discovery chemistry and molecular technologies, Drug Discovery Research, Bristol-Myers Squibb Company

2:00 p.m.   Center for Study of Hepatitis C
Hep C Seminar: Mechanisms of RIG-I–like Receptor Activation and Manipulation by Viral Pathogens

Michaela U. Gack, Ph.D., professor, department of microbiology, University of Chicago

 Tuesday, April 11, 2017
4:00 p.m.   Other Tri-Institutional Events
Images of Inflammatory Cell Death

Guy Salvesen, Ph.D., professor, Tumor Microenvironment and Cancer Immunology Program, dean, Graduate School of Biomedical Sciences, associate director, education and mentoring, SBP Cancer Center, Sanford Burnham Prebys Medical Discovery Institute

4:00 p.m.   Center for Studies in Physics and Biology Seminars
On the Evolution of Leukemia

Dan Landau, Ph.D., assistant professor, Joan and Sanford I. Weill Department of Medicine and department of physiology and biophysics, Weill Cornell Medical College

 Wednesday, April 12, 2017
1:00 p.m.   Other Lectures, Seminars and Symposia
Marina Caskey, Public Seminar
Clinical Evaluation of anti-HIV-1 Broadly Neutralizing Antibodies: 3BNC117 and 10-1074

Marina Caskey, M.D., Assistant Professor of Clinical Investigation, The Rockefeller University, Clinical Evaluation of anti-HIV-1 Broadly Neutralizing Antibodies: 3BNC117 and 10-1074

4:00 p.m.   Other Campus Events
SMART IRB Webinar
 Thursday, April 13, 2017
2:00 p.m.   Other Tri-Institutional Events
Capturing Principles of Tissue Function by Imaging the Skin of Live Mice

Valentina Greco, Ph.D., associate professor, department of genetics, Yale University

2:00 p.m.   Thesis Presentations
What’s in a Message? RNA Editing and the New Frontier of Epitranscriptomics

Violeta Rayon Estrada, graduate fellow, The Rockefeller University

4:00 p.m.   Center for Studies in Physics and Biology Seminars
Statistical Mechanics of Stem Cells

Sidhartha Goyal, Ph.D., assistant professor, department of physics, University of Toronto

 Friday, April 14, 2017
3:45 p.m.   Friday Lecture Series
Canceled

Canceled - Tom Maniatis, Ph.D., Isidore S. Edelman Professor and chair, department of biochemistry and molecular biophysics, Columbia University Medical Center

 Monday, April 17, 2017
10:00 a.m.   Thesis Presentations
A Neuronal Circuit Architecture for Angular Integration in Drosophila melanogaster

Jonathan Green, graduate fellow, The Rockefeller University

12:00 p.m.   Other Tri-Institutional Events
Imaging Immunity

Hidde Ploegh, Ph.D., professor, department of biology, Massachusetts Institute of Technology

1:30 p.m.   Other Tri-Institutional Events
Reprogramming B Cell Memory

Michael McHeyzer-Williams, Ph.D., professor, department of immunology and microbiology, California campus, The Scripps Research Institute

 Tuesday, April 18, 2017
4:00 p.m.   Other Tri-Institutional Events
New Approaches to Drug and Gene Delivery for Cancer

Justin Hanes, Ph.D., Professor, Lewis J. Ort Professor of Ophthalmology, Biomedical Engineering, Chemical & Biomolecular Engineering, Environmental Health Sciences, Neurosurgery, Oncology, and Pharmacology & Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD

4:00 p.m.   Center for Studies in Physics and Biology Seminars
Protein Pattern Formation: Rethinking Nonlinear Dynamics

Erwin Frey, Ph.D., professor and chair, statistical and biological physics, University of Munich

 Thursday, April 20, 2017
10:30 a.m.   Other Tri-Institutional Events
Spatial Genomics: Single-cell In Situ Expression and Lineage Analysis

Long Cai, Ph.D., assistant professor, division of chemistry and chemical engineering, California Institute of Technology

10:30 a.m.   Thesis Presentations
The FOXC Business of Sticking Together: Maintaining Stem Cell Quiescence and Adhesion for Long-term Hair Follicle Regeneration

Kenneth Lay, graduate fellow, The Rockefeller University

12:00 p.m.   Chemical Biology Seminar Series
Super-resolution Microscopy Made Simple

Joshua Vaughan, Ph.D., assistant professor, department of chemistry, University of Washington

2:00 p.m.   Other Tri-Institutional Events
Massive Scale Brain Informatics

Hanchuan Peng, Ph.D., associate investigator and head, computational neuroanatomy and smart imaging group, Allen Institute for Brain Science

2:30 p.m.   Thesis Presentations
Bullets from a Gun: Engineered Antimicrobial Peptides from a Phage Lysin to Fight Acinetobacter baumannii

Mya Thandar, graduate fellow, The Rockefeller University

8:00 p.m.   Harvey Society
Navigating the Cellular Landscape with New Imaging Technologies

Jennifer Lippincott-Schwartz, Ph.D., group leader, Janelia Research Campus, Howard Hughes Medical Institute

 Friday, April 21, 2017
11:00 a.m.   Thesis Presentations
Deconvoluting Cell-type Specific 3'UTR Isoform Expression in the Adult and Developing Cerebellum

Sasa Jereb, Graduate Fellow, The Rockefeller University

3:00 p.m.   Other Tri-Institutional Events
Replicating DNA with Artificial Nucleotides: A Chemical Basis for Mutagenesis and Alkylation Mapping

Shana Sturla, Ph.D., professor, department of health sciences and technology, Swiss Federal Institute of Technology in Zurich

3:45 p.m.   Friday Lecture Series
The Epigenetic Dynamics of X-chromosome Inactivation: Fine-tuning Gene Dosage during Development
The Richard M. Furlaud Distinguished Lecture

Edith Heard, Ph.D., professor and chair, epigenetics and cellular memory, Collège de France; director, department of genetics and developmental biology, Institut Curie

 Monday, April 24, 2017
1:30 p.m.   Other Tri-Institutional Events
Endogenous Barcoding for Tissue Deconvolution

Hans-Reimer Rodewald, Ph.D., DVM, head, division for cellular immunology, German Cancer Research Center (DKFZ)

 Tuesday, April 25, 2017
4:00 p.m.   Other Tri-Institutional Events
Taming a Protein Destruction Machine: CUL4 Structure, Function, and Regulation

Nicolas Thomä, Ph.D., senior group leader, structural biology, Friedrich Miescher Institute for Biomedical Research

4:00 p.m.   Center for Studies in Physics and Biology Seminars
Data-driven Discovery of Governing Equations in the Engineering, Physical, and Biological Sciences

J. Nathan Kutz, Ph.D., Robert Bolles and Yasuko Endo Professor, department of applied mathematics, University of Washington

4:00 p.m.   Other Tri-Institutional Events
The Road to RNAi Therapeutics: Tackling a Billion-year-old Barrier with New siRNN Chemistry

Steven Dowdy, Ph.D., professor, department of cellular and molecular medicine, University of California, San Diego, School of Medicine

5:00 p.m.   Center for Study of Hepatitis C
Hep C Seminar: How to Build a Poxvirus in Super-resolution

Jason Mercer, Ph.D., professor, Medical Research Council Laboratory for Molecular Cell Biology, University College London

 Wednesday, April 26, 2017
2:00 p.m.   Other Tri-Institutional Events
Endoplasmic Reticulum Stress in the Drosophila Eye

Pedro Domingos, Ph.D., principal investigator, Laboratory of Cell Signaling in Drosophila, ITQB NOVA

4:30 p.m.   MSKCC President's Research Seminar
Engineering the Cancer Genome

Tyler Jacks, Ph.D., David H. Koch Professor, director, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; investigator, Howard Hughes Medical Institute

 Thursday, April 27, 2017
2:00 p.m.   Other Lectures, Seminars and Symposia
iRIS Users Group Meeting
2:00 p.m.   Cell Biology Seminars
Imaging Phagocytosis: Role of Receptors, Integrins, and the Cytoskeleton

Sergio Grinstein, Ph.D., senior scientist, cell biology, The Hospital for Sick Children; professor, department of biochemistry, University of Toronto

4:00 p.m.   Center for Studies in Physics and Biology Seminars
Transient Symmetry and Self-similarity in Proteins: A Protein Structure Theory

Lawrence Williams, Ph.D., professor, department of chemistry and chemical biology, Rutgers University

 Friday, April 28, 2017
3:45 p.m.   Friday Lecture Series
The Surprising Chemistry of Nonenzymatic RNA Replication

Jack W. Szostak, Ph.D., professor of genetics, Harvard Medical School, professor of chemistry and chemical biology, Harvard University; Alex A. Rich Distinguished Investigator, department of molecular biology, Massachusetts General Hospital; investigator, Howard Hughes Medical Institute

 Monday, May 1, 2017
12:00 p.m.   Wellness Lecture Series
OcD, cHaOs, pLaCeBoS, PiLLs, and WILL
A Case of Obsessive Compulsive

Engin Ozertugrul, Ph.D., psychologist, The Rockefeller University

1:30 p.m.   Other Tri-Institutional Events
Division of Labor among the Subunits of a Highly Coordinated Ring ATPase

Carlos Bustamante, Ph.D., professor and Raymond and Beverly Sackler Chair of Biophysics, department of molecular and cell biology, department of physics, and department of chemistry, University of California, Berkeley

3:00 p.m.   Other Tri-Institutional Events
Chromatin Regulation and Genome Maintenance by Mammalian Sirtuins

Katrin Chua, M.D., Ph.D., associate professor, division of endocrinology, gerontology, and metabolism, department of medicine, associate director, Medical Scientist Training Program, Stanford University School of Medicine

 Tuesday, May 2, 2017
4:00 p.m.   Center for Studies in Physics and Biology Seminars
The Folding Cooperativity of a Protein is Controlled by the Topology of Its Polypeptide Chain

Carlos Bustamante, Ph.D., Raymond and Beverly Sackler Professor in Biophysics, department of chemistry, department of physics, and department of molecular and cell biology, University of California, Berkeley

5:00 p.m.   Center for Study of Hepatitis C
Novel Therapeutic Approaches to Target Hepatitis B and Hepatitis D Virus Infection

Stephan Urban, Ph.D., professor, department of infectious diseases, Heidelberg University

 Wednesday, May 3, 2017
4:30 p.m.   MSKCC President's Research Seminar
Signatures of Mutational Processes in Human Cancer

Sir Michael Stratton, FMedSci, chief executive officer, Wellcome Genome Campus, director, Wellcome Trust Sanger Institute

 Thursday, May 4, 2017
10:30 a.m.   Other Tri-Institutional Events
Single-cell Approaches to Dissect Mechanisms for Epigenetic Memory

Amos Tanay, Ph.D., associate professor, department of computer science and applied mathematics, Weizmann Institute of Science

2:00 p.m.   Other Tri-Institutional Events
The Molecular Biology of Meiosis

Scott Hawley, Ph.D., investigator and American Cancer Society Research Professor, dean, The Graduate School of the Stowers Institute, Stowers Institute for Medical Research

 Friday, May 5, 2017
10:30 a.m.   Cell Biology Seminars
Centrosomal Proteins Mutated in Human Inherited Retinal Disorders
Hidden Genetic Variation: Hereditary Blindness as a Model

Elfride De Baere, Ph.D., professor, Center for Medical Genetics, Ghent University Hospital

1:00 p.m.   Thesis Presentations
How Does Light Stimulate Sensory Hair Cells?

Julien Azimzadeh, biomedical fellow, The Rockefeller University

3:45 p.m.   Friday Lecture Series
Sensing Tension at Kinetochores

Sue Biggins, Ph.D., member and associate director, division of basic sciences, Fred Hutchinson Cancer Research Center; investigator, Howard Hughes Medical Institute